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Deficits in dopaminergic transmission precede neuron loss and dysfunction in a new Parkinson model

The pathological end-state of Parkinson disease is well described from postmortem tissue, but there remains a pressing need to define early functional changes to susceptible neurons and circuits. In particular, mechanisms underlying the vulnerability of the dopamine neurons of the substantia nigra p...

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Detalhes bibliográficos
Main Authors: Janezic, Stephanie, Threlfell, Sarah, Dodson, Paul D., Dowie, Megan J., Taylor, Tonya N., Potgieter, Dawid, Parkkinen, Laura, Senior, Steven L., Anwar, Sabina, Ryan, Brent, Deltheil, Thierry, Kosillo, Polina, Cioroch, Milena, Wagner, Katharina, Ansorge, Olaf, Bannerman, David M., Bolam, J. Paul, Magill, Peter J., Cragg, Stephanie J., Wade-Martins, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3801069/
https://ncbi.nlm.nih.gov/pubmed/24082145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1309143110
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