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Increased striatal dopamine release and hyperdopaminergic-like behaviour in mice lacking both alpha-synuclein and gamma-synuclein

Alpha-synuclein is intimately involved in the pathogenesis of Parkinson’s disease, and has been implicated in the regulation of synthesis, release and reuptake of dopamine. However, mice lacking members of the synuclein family have been reported to display no overt behavioural phenotype. This may be...

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Detalhes bibliográficos
Main Authors: Senior, Steven L., Ninkina, Natalia, Deacon, Robert, Bannerman, David, Buchman, Vladimir L., Cragg, Stephanie J., Wade-Martins, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145106/
https://ncbi.nlm.nih.gov/pubmed/18333965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2008.06055.x
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