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α-Synuclein and dopamine at the crossroads of Parkinson’s disease

α-Synuclein is central to the Lewy body neuropathology of Parkinson’s disease (PD), a devastating neurodegenerative disorder characterized by numerous motor and non-motor manifestations. The cardinal motor symptoms are linked to death of dopaminergic neurons in the nigrostriatal pathway. Here we ask...

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Main Authors: Venda, Lara Lourenço, Cragg, Stephanie J., Buchman, Vladimir L., Wade-Martins, Richard
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631137/
https://ncbi.nlm.nih.gov/pubmed/20961626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tins.2010.09.004
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