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α-Synuclein and dopamine at the crossroads of Parkinson’s disease
α-Synuclein is central to the Lewy body neuropathology of Parkinson’s disease (PD), a devastating neurodegenerative disorder characterized by numerous motor and non-motor manifestations. The cardinal motor symptoms are linked to death of dopaminergic neurons in the nigrostriatal pathway. Here we ask...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3631137/ https://ncbi.nlm.nih.gov/pubmed/20961626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tins.2010.09.004 |
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