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The effect of α-synuclein knockdown on MPP+ toxicity in models of human neurons
The protein α-synuclein is central to the pathophysiology of Parkinson’s disease (PD) but its role in the development of neurodegeneration remains unclear. α-synuclein knockout mice develop without gross abnormality and are resistant to MPTP, a mitochondrial inhibitor widely used to model parkinsoni...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3132457/ https://ncbi.nlm.nih.gov/pubmed/19032594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2008.06527.x |
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