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Increased striatal dopamine release and hyperdopaminergic-like behaviour in mice lacking both alpha-synuclein and gamma-synuclein

Alpha-synuclein is intimately involved in the pathogenesis of Parkinson’s disease, and has been implicated in the regulation of synthesis, release and reuptake of dopamine. However, mice lacking members of the synuclein family have been reported to display no overt behavioural phenotype. This may be...

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Main Authors: Senior, Steven L., Ninkina, Natalia, Deacon, Robert, Bannerman, David, Buchman, Vladimir L., Cragg, Stephanie J., Wade-Martins, Richard
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145106/
https://ncbi.nlm.nih.gov/pubmed/18333965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2008.06055.x
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