A carregar...
Binding of longer Aβ to transmembrane domain 1 of presenilin 1 impacts on Aβ42 generation
BACKGROUND: Amyloid-β peptide ending at 42nd residue (Aβ42) is believed as a pathogenic peptide for Alzheimer disease. Although γ-secretase is a responsible protease to generate Aβ through a processive cleavage, the proteolytic mechanism of γ-secretase at molecular level is poorly understood. RESULT...
Na minha lista:
| Main Authors: | , , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3896738/ https://ncbi.nlm.nih.gov/pubmed/24410857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-9-7 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|