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MIR29B regulates expression of MLLT11 (AF1Q), an MLL fusion partner, and low MIR29B expression associates with adverse cytogenetics and poor overall survival in AML

MLLT11, an MLL fusion partner, is a poor prognostic biomarker for paediatric acute myeloid leukaemia (AML), adult normal cytogenetics AML, and adult myelodysplastic syndrome. MLLT11 is highly regulated during haematopoietic progenitor differentiation and development but its regulatory mechanisms hav...

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Détails bibliographiques
Auteurs principaux: Xiong, Yin, Li, Zejuan, Ji, Min, Tan, Aik-Choon, Bemis, Judson, Tse, Jove-Victor, Huang, Gang, Park, Jino, Ji, Chunyan, Chen, Jianjun, Bemis, Lynne T., Bunting, Kevin D., Tse, William
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896048/
https://ncbi.nlm.nih.gov/pubmed/21496004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2141.2011.08662.x
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