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MIR29B regulates expression of MLLT11 (AF1Q), an MLL fusion partner, and low MIR29B expression associates with adverse cytogenetics and poor overall survival in AML

MLLT11, an MLL fusion partner, is a poor prognostic biomarker for paediatric acute myeloid leukaemia (AML), adult normal cytogenetics AML, and adult myelodysplastic syndrome. MLLT11 is highly regulated during haematopoietic progenitor differentiation and development but its regulatory mechanisms hav...

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Bibliografiska uppgifter
Huvudupphovsmän: Xiong, Yin, Li, Zejuan, Ji, Min, Tan, Aik-Choon, Bemis, Judson, Tse, Jove-Victor, Huang, Gang, Park, Jino, Ji, Chunyan, Chen, Jianjun, Bemis, Lynne T., Bunting, Kevin D., Tse, William
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896048/
https://ncbi.nlm.nih.gov/pubmed/21496004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2141.2011.08662.x
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