MIR29B regulates expression of MLLT11 (AF1Q), an MLL fusion partner, and low MIR29B expression associates with adverse cytogenetics and poor overall survival in AML

MLLT11, an MLL fusion partner, is a poor prognostic biomarker for paediatric acute myeloid leukaemia (AML), adult normal cytogenetics AML, and adult myelodysplastic syndrome. MLLT11 is highly regulated during haematopoietic progenitor differentiation and development but its regulatory mechanisms hav...

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Bibliografiske detaljer
Main Authors: Xiong, Yin, Li, Zejuan, Ji, Min, Tan, Aik-Choon, Bemis, Judson, Tse, Jove-Victor, Huang, Gang, Park, Jino, Ji, Chunyan, Chen, Jianjun, Bemis, Lynne T., Bunting, Kevin D., Tse, William
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896048/
https://ncbi.nlm.nih.gov/pubmed/21496004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2141.2011.08662.x
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