Thioridazine requires calcium influx to induce MLL-AF6–rearranged AML cell death

In pediatric acute myeloid leukemia (AML), intensive chemotherapy and allogeneic hematopoietic stem cell transplantation are the cornerstones of treatment in high-risk cases, with severe late effects and a still high risk of disease recurrence as the main drawbacks. The identification of targeted, m...

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Dettagli Bibliografici
Pubblicato in:Blood Adv
Autori principali: Tregnago, Claudia, Da Ros, Ambra, Porcù, Elena, Benetton, Maddalena, Simonato, Manuela, Simula, Luca, Borella, Giulia, Polato, Katia, Minuzzo, Sonia, Borile, Giulia, Cogo, Paola, Campello, Silvia, Massi, Alessandro, Romagnoli, Romeo, Buldini, Barbara, Locatelli, Franco, Pigazzi, Martina
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2020
Soggetti:
Myeloid Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7509857/
https://ncbi.nlm.nih.gov/pubmed/32931582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002001
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