NPM1 Mutational Status Underlines Different Biological Features in Pediatric AML

SIMPLE SUMMARY: Nucleophosmin (NPM1) protein regulates several cellular processes and is predominantly located in the nucleolus, owing to the localization signal provided by two tryptophan residues. In acute myeloid leukemia (AML), NPM1 gene is frequently mutated, leading to the aberrant translocati...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Tregnago, Claudia, Benetton, Maddalena, Padrin, Davide, Polato, Katia, Borella, Giulia, Da Ros, Ambra, Marchetti, Anna, Porcù, Elena, Del Bufalo, Francesca, Mecucci, Cristina, Locatelli, Franco, Pigazzi, Martina
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8304368/
https://ncbi.nlm.nih.gov/pubmed/34298672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13143457
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