NPM1 Mutational Status Underlines Different Biological Features in Pediatric AML

SIMPLE SUMMARY: Nucleophosmin (NPM1) protein regulates several cellular processes and is predominantly located in the nucleolus, owing to the localization signal provided by two tryptophan residues. In acute myeloid leukemia (AML), NPM1 gene is frequently mutated, leading to the aberrant translocati...

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Publicado en:Cancers (Basel)
Autores principales: Tregnago, Claudia, Benetton, Maddalena, Padrin, Davide, Polato, Katia, Borella, Giulia, Da Ros, Ambra, Marchetti, Anna, Porcù, Elena, Del Bufalo, Francesca, Mecucci, Cristina, Locatelli, Franco, Pigazzi, Martina
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2021
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8304368/
https://ncbi.nlm.nih.gov/pubmed/34298672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13143457
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