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Expression of MLL-AF4 or AF4-MLL fusions does not impact the efficiency of DNA damage repair
The most frequent rearrangement of the human MLL gene fuses MLL to AF4 resulting in high-risk infant B-cell acute lymphoblastic leukemia (B-ALL). MLL fusions are also hallmark oncogenic events in secondary acute myeloid leukemia. They are a direct consequence of mis-repaired DNA double strand breaks...
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| 出版年: | Oncotarget |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Impact Journals LLC
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5058691/ https://ncbi.nlm.nih.gov/pubmed/27119507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8938 |
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