Revisiting the biology of infant t(4;11)/MLL-AF4(+) B-cell acute lymphoblastic leukemia

Infant B-cell acute lymphoblastic leukemia (B-ALL) accounts for 10% of childhood ALL. The genetic hallmark of most infant B-ALL is chromosomal rearrangements of the mixed-lineage leukemia (MLL) gene. Despite improvement in the clinical management and survival (∼85-90%) of childhood B-ALL, the outcom...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Blood
Prif Awduron: Sanjuan-Pla, Alejandra, Bueno, Clara, Prieto, Cristina, Acha, Pamela, Stam, Ronald W., Marschalek, Rolf, Menéndez, Pablo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2015
Pynciau:
Review Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683329/
https://ncbi.nlm.nih.gov/pubmed/26463423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-09-667378
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