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Revisiting the biology of infant t(4;11)/MLL-AF4(+) B-cell acute lymphoblastic leukemia
Infant B-cell acute lymphoblastic leukemia (B-ALL) accounts for 10% of childhood ALL. The genetic hallmark of most infant B-ALL is chromosomal rearrangements of the mixed-lineage leukemia (MLL) gene. Despite improvement in the clinical management and survival (∼85-90%) of childhood B-ALL, the outcom...
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| Publicado no: | Blood |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4683329/ https://ncbi.nlm.nih.gov/pubmed/26463423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-09-667378 |
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