Lataa...
Mutation of Y407 in the CH3 domain dramatically alters glycosylation and structure of human IgG
Antibody engineering is increasingly being used to influence the properties of monoclonal antibodies to improve their biotherapeutic potential. One important aspect of this is the modulation of glycosylation as a strategy to improve efficacy. Here, we describe mutations of Y407 in the CH3 domain of...
Tallennettuna:
| Päätekijät: | , , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Landes Bioscience
2013
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3893232/ https://ncbi.nlm.nih.gov/pubmed/23406897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.23532 |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|