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Identification of Two HIV Inhibitors that also Inhibit Human RNaseH2

A total of 140,000 compounds were screened in a targetfree cell-based high throughput assay against HIV-1 infection, and a subset of 81 promising compounds was identified. Secondary screening of these 81 compounds revealed two putative human RNaseH2 inhibitors, RHI001 and RHI002, with IC50 value of...

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Autors principals: Kim, Junghwan, Yoon, Jaewan, Ju, MoonKyeong, Lee, Yunmi, Kim, Tae-Hee, Kim, Junwon, Sommer, Peter, No, Zaesung, Cechetto, Jonathan, Han, Sung-Jun
Format: Artigo
Idioma:Inglês
Publicat: Korea Society for Molecular and Cellular Biology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887976/
https://ncbi.nlm.nih.gov/pubmed/24008364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10059-013-2348-z
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