Identification of a Novel Sulfonamide Non-Nucleoside Reverse Transcriptase Inhibitor by a Phenotypic HIV-1 Full Replication Assay

Classical target-based, high-throughput screening has been useful for the identification of inhibitors for known molecular mechanisms involved in the HIV life cycle. In this study, the development of a cell-based assay that uses a phenotypic drug discovery approach based on automated high-content sc...

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Detalhes bibliográficos
Main Authors: Kim, Tae-Hee, Ko, Yoonae, Christophe, Thierry, Cechetto, Jonathan, Kim, Junwon, Kim, Kyoung-Ae, Boese, Annette S., Garcia, Jean-Michel, Fenistein, Denis, Ju, Moon Kyeong, Kim, Junghwan, Han, Sung-Jun, Kwon, Ho Jeong, Brondani, Vincent, Sommer, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715523/
https://ncbi.nlm.nih.gov/pubmed/23874756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068767
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