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Identification of Two HIV Inhibitors that also Inhibit Human RNaseH2
A total of 140,000 compounds were screened in a targetfree cell-based high throughput assay against HIV-1 infection, and a subset of 81 promising compounds was identified. Secondary screening of these 81 compounds revealed two putative human RNaseH2 inhibitors, RHI001 and RHI002, with IC50 value of...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Korea Society for Molecular and Cellular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3887976/ https://ncbi.nlm.nih.gov/pubmed/24008364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10059-013-2348-z |
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