Discovery of Phenylaminopyridine Derivatives as Novel HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors

[Image: see text] We identified a novel class of aryl-substituted triazine compounds as potent non-nucleoside reverse transcriptase inhibitors (NNRTIs) during a high-throughput screening campaign that evaluated more than 200000 compounds for antihuman immunodeficiency virus (HIV) activity using a ce...

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Main Authors: Kim, Junwon, Lee, Doohyun, Park, Changmin, So, Wonyoung, Jo, Mina, Ok, Taedong, Kwon, Jeongjin, Kong, Sunju, Jo, Suyeon, Kim, Youngmi, Choi, Jihyun, Kim, Hyoung Cheul, Ko, Yoonae, Choi, Inhee, Park, Youngsam, Yoon, Jaewan, Ju, Moon Kyeong, Kim, Junghwan, Han, Sung-Jun, Kim, Tae-Hee, Cechetto, Jonathan, Nam, Jiyoun, Sommer, Peter, Liuzzi, Michel, Lee, Jinhwa, No, Zaesung
格式: Artigo
語言:Inglês
出版: American Chemical Society 2012
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4025836/
https://ncbi.nlm.nih.gov/pubmed/24900529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300146q
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