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dRAGging Amino Acid-mTORC1 Signaling by SH3BP4
Mammalian target of rapamycin complex 1 (mTORC1) is a master regulator of cell growth and autophagy. Its activity is regulated by the availability of amino acids and growth factors. The activation of mTORC1 by growth factors, such as insulin and insulin-like growth factor-1 (IGF-1), is mediated by t...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Korea Society for Molecular and Cellular Biology
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3887856/ https://ncbi.nlm.nih.gov/pubmed/23274731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10059-013-2249-1 |
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