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dRAGging Amino Acid-mTORC1 Signaling by SH3BP4

Mammalian target of rapamycin complex 1 (mTORC1) is a master regulator of cell growth and autophagy. Its activity is regulated by the availability of amino acids and growth factors. The activation of mTORC1 by growth factors, such as insulin and insulin-like growth factor-1 (IGF-1), is mediated by t...

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Autori principali: Kim, Young-Mi, Kim, Do-Hyung
Natura: Artigo
Lingua:Inglês
Pubblicazione: Korea Society for Molecular and Cellular Biology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887856/
https://ncbi.nlm.nih.gov/pubmed/23274731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10059-013-2249-1
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