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An expanded role for mTORC1 in autophagy
Mechanistic target of rapamycin complex 1 (mTORC1) negatively regulates autophagy at early stages by phosphorylating Unc51-like kinase 1 (ULK1). Our recent study expanded the roles of mTORC1 in autophagy by identifying ultraviolet radiation resistance-associated gene product (UVRAG) as a substrate o...
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| Publicado no: | Mol Cell Oncol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4845164/ https://ncbi.nlm.nih.gov/pubmed/27308528 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1010958 |
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