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Interleukin-1β sequesters hypoxia inducible factor 2α to the primary cilium

BACKGROUND: The primary cilium coordinates signalling in development, health and disease. Previously we have shown that the cilium is essential for the anabolic response to loading and the inflammatory response to interleukin-1β (IL-1β). We have also shown the primary cilium elongates in response to...

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Detalhes bibliográficos
Main Authors: Wann, Angus KT, Thompson, Clare L, Chapple, J Paul, Knight, Martin M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3886195/
https://ncbi.nlm.nih.gov/pubmed/24330727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2046-2530-2-17
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