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The primary cilium influences interleukin-1β-induced NFκB signalling by regulating IKK activity

The primary cilium is an organelle acting as a master regulator of cellular signalling. We have previously shown that disruption of primary cilia assembly, through targeting intraflagellar transport, is associated with muted nitric oxide and prostaglandin responses to the inflammatory cytokine inter...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wann, A.K.T., Chapple, J.P., Knight, M.M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier Science Ltd 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064300/
https://ncbi.nlm.nih.gov/pubmed/24726893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2014.04.004
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