Astrocyte IKKβ/NF-κB signaling is required for diet-induced obesity and hypothalamic inflammation

OBJECTIVE: Obesity and high fat diet (HFD) consumption in rodents is associated with hypothalamic inflammation and reactive gliosis. While neuronal inflammation promotes HFD-induced metabolic dysfunction, the role of astrocyte activation in susceptibility to hypothalamic inflammation and diet-induce...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Douglass, J.D., Dorfman, M.D., Fasnacht, R., Shaffer, L.D., Thaler, J.P.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5369266/
https://ncbi.nlm.nih.gov/pubmed/28377875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.01.010
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