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Interleukin-1β sequesters hypoxia inducible factor 2α to the primary cilium

BACKGROUND: The primary cilium coordinates signalling in development, health and disease. Previously we have shown that the cilium is essential for the anabolic response to loading and the inflammatory response to interleukin-1β (IL-1β). We have also shown the primary cilium elongates in response to...

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Bibliografiske detaljer
Main Authors: Wann, Angus KT, Thompson, Clare L, Chapple, J Paul, Knight, Martin M
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3886195/
https://ncbi.nlm.nih.gov/pubmed/24330727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2046-2530-2-17
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