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Polycystin-2 Is Required for Chondrocyte Mechanotransduction and Traffics to the Primary Cilium in Response to Mechanical Stimulation

Primary cilia and associated intraflagellar transport are essential for skeletal development, joint homeostasis, and the response to mechanical stimuli, although the mechanisms remain unclear. Polycystin-2 (PC2) is a member of the transient receptor potential polycystic (TRPP) family of cation chann...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Thompson, Clare L., McFie, Megan, Chapple, J. Paul, Beales, Philip, Knight, Martin M.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8122406/
https://ncbi.nlm.nih.gov/pubmed/33919210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22094313
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