Structural Determinants of the 5′-Methylthioinosine Specificity of Plasmodium Purine Nucleoside Phosphorylase

Plasmodium parasites rely upon purine salvage for survival. Plasmodium purine nucleoside phosphorylase is part of the streamlined Plasmodium purine salvage pathway that leads to the phosphorylysis of both purines and 5′-methylthiopurines, byproducts of polyamine synthesis. We have explored structura...

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Bibliografski detalji
Glavni autori: Donaldson, Teraya M., Ting, Li-Min, Zhan, Chenyang, Shi, Wuxian, Zheng, Renjian, Almo, Steven C., Kim, Kami
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885546/
https://ncbi.nlm.nih.gov/pubmed/24416224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084384
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