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Attenuated Plasmodium yoelii lacking purine nucleoside phosphorylase confer protective immunity
Malaria continues to devastate sub-Saharan Africa owing to the emergence of drug resistance to established antimalarials and to the lack of an efficacious vaccine. Plasmodium species have a unique streamlined purine pathway in which the dual specificity enzyme purine nucleoside phosphorylase (PNP) f...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3937818/ https://ncbi.nlm.nih.gov/pubmed/18758447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.1867 |
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