Plasmodium falciparum Purine Nucleoside Phosphorylase Is Critical for Viability of Malaria Parasites

Human malaria infections resulting from Plasmodium falciparum have become increasingly difficult to treat due to the emergence of drug-resistant parasites. The P. falciparum purine salvage enzyme purine nucleoside phosphorylase (PfPNP) is a potential drug target. Previous studies, in which PfPNP was...

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Bibliografiske detaljer
Main Authors: Madrid, Dennis C., Ting, Li-Min, Waller, Karena L., Schramm, Vern L., Kim, Kami
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2008
Fag:
Metabolism and Bioenergetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2602904/
https://ncbi.nlm.nih.gov/pubmed/18957439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807218200
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