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Genetic resistance to purine nucleoside phosphorylase inhibition in Plasmodium falciparum

Plasmodium falciparum causes the most lethal form of human malaria and is a global health concern. The parasite responds to antimalarial therapies by developing drug resistance. The continuous development of new antimalarials with novel mechanisms of action is a priority for drug combination therapi...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Ducati, Rodrigo G., Namanja-Magliano, Hilda A., Harijan, Rajesh K., Fajardo, J. Eduardo, Fiser, Andras, Daily, Johanna P., Schramm, Vern L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834662/
https://ncbi.nlm.nih.gov/pubmed/29440412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1525670115
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