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Transition-state inhibitors of purine salvage and other prospective enzyme targets in malaria
Malaria is a leading cause of human death within the tropics. The gradual generation of drug resistance imposes an urgent need for the development of new and selective antimalarial agents. Kinetic isotope effects coupled to computational chemistry have provided the relevant details on geometry and c...
Tallennettuna:
| Päätekijät: | , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3819805/ https://ncbi.nlm.nih.gov/pubmed/23859211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.13.51 |
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