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New potent and selective polyfluoroalkyl ketone inhibitors of GVIA calcium-independent phospholipase A2

Group VIA calcium-independent phospholipase A(2) (GVIA iPLA(2)) has recently emerged as an important pharmaceutical target. Selective and potent GVIA iPLA(2) inhibitors can be used to study its role in various neurological disorders. In the current work, we explore the significance of the introducti...

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Detalhes bibliográficos
Main Authors: Magrioti, Victoria, Nikolaou, Aikaterini, Smyrniotou, Annetta, Shah, Ishita, Constantinou-Kokotou, Violetta, Dennis, Edward A., Kokotos, George
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883354/
https://ncbi.nlm.nih.gov/pubmed/23916152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.07.010
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