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Synthesis of 2-oxoamides based on sulfonamide analogues of γ-amino acids and their activity on phospholipase A(2)
A variety of lipophilic 2-oxoamides containing sulfonamide analogues of γ-amino acids as well as acyl sulfonamides of γ-aminobutyric acid were synthesized. Their ability to inhibit intracellular GIVA cPLA(2) and GVIA iPLA(2) as well as secreted GV sPLA(2) was evaluated. The sulfonamide group seems a...
Gorde:
| Egile Nagusiak: | , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2008
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2678953/ https://ncbi.nlm.nih.gov/pubmed/18618424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psc.1048 |
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