Chargement en cours...
Systemic resistance to methotrexate in transgenic mice carrying a mutant dihydrofolate reductase gene.
A full-length cDNA coding for a mutant dihydrofolate reductase (DHFR; 5,6,7,8-tetrahydrofolate: NADP+ oxidoreductase, EC 1.5.1.3), cloned from a mouse fibroblast cell line grown in high concentrations of methotrexate (MTX), was microinjected into mouse embryos to produce transgenic mice. The DHFR cD...
Enregistré dans:
| Auteurs principaux: | , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
1986
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC387192/ https://ncbi.nlm.nih.gov/pubmed/3467329 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|