Mutations in the dihydrofolate reductase gene of trimethoprim-resistant isolates of Streptococcus pneumoniae.

Streptococcus pneumoniae isolates resistant to several antimicrobial agent classes including trimethoprim-sulfamethoxazole have been reported with increasing frequency throughout the world. The MICs of trimethoprim, sulfamethoxazole, and trimethoprim-sulfamethoxazole (1:19) for 259 clinical isolates...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Adrian, P V, Klugman, K P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164136/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9371341/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.11.2406
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