Isolation and characterization of dihydrofolate reductase from trimethoprim-susceptible and trimethoprim-resistant Pseudomonas cepacia.

Trimethoprim resistance was investigated in cystic fibrosis isolates of Pseudomonas cepacia. Determination of the MIC of trimethoprim for 111 strains revealed at least two populations of resistant organisms, suggesting the presence of more than one mechanism of resistance. Investigation of the antib...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Burns, J L, Lien, D M, Hedin, L A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1989
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172634/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2802552/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.8.1247
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