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Isolation and characterization of dihydrofolate reductase from trimethoprim-susceptible and trimethoprim-resistant Pseudomonas cepacia.

Trimethoprim resistance was investigated in cystic fibrosis isolates of Pseudomonas cepacia. Determination of the MIC of trimethoprim for 111 strains revealed at least two populations of resistant organisms, suggesting the presence of more than one mechanism of resistance. Investigation of the antib...

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Burns, J L, Lien, D M, Hedin, L A
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1989
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172634/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2802552/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.8.1247
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