Nonsense mutations in the dihydrofolate reductase gene affect RNA processing.
Steady-state dihydrofolate reductase (dhfr) mRNA levels were decreased as a result of nonsense mutations in the dhfr gene. Thirteen DHFR-deficient mutants were isolated after treatment of Chinese hamster ovary cells with UV irradiation. The positions of most point mutations were localized by RNA het...
محفوظ في:
| الحاوية / القاعدة: | Mol Cell Biol |
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| المؤلفون الرئيسيون: | , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Taylor & Francis
1989
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362753/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2779551/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.7.2868-2880.1989 |
| الوسوم: |
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