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(13)C-Methyl isocyanide as an NMR probe for cytochrome P450 active sites
The cytochromes P450 (CYPs) play a central role in many biologically important oxidation reactions, including the metabolism of drugs and other xenobiotic compounds. Because they are often assayed as both drug targets and anti-targets, any tools that provide: (a) confirmation of active site binding...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3870883/ https://ncbi.nlm.nih.gov/pubmed/19199046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-009-9300-8 |
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