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(13)C-Methyl isocyanide as an NMR probe for cytochrome P450 active sites

The cytochromes P450 (CYPs) play a central role in many biologically important oxidation reactions, including the metabolism of drugs and other xenobiotic compounds. Because they are often assayed as both drug targets and anti-targets, any tools that provide: (a) confirmation of active site binding...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: McCullough, Christopher R., Pullela, Phani Kumar, Im, Sang-Choul, Waskell, Lucy, Sem, Daniel S.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870883/
https://ncbi.nlm.nih.gov/pubmed/19199046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-009-9300-8
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