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The Synthesis, Characterization, and Application of (13)C-Methyl Isocyanide as an NMR Probe of Heme Protein Active Sites
The cytochromes P450 (CYPs) play a central role in a variety of important biological oxidations, such as steroid synthesis and the metabolism of xenobiotic compounds, including most drugs. Because CYPs are frequently assayed as drug targets or as anti-targets, tools that provide confirmation of acti...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4057429/ https://ncbi.nlm.nih.gov/pubmed/23475666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-321-3_4 |
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