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Differential actions of orexin receptors in brainstem cholinergic and monoaminergic neurons revealed by receptor knockouts: implications for orexinergic signaling in arousal and narcolepsy
Orexin neuropeptides influence multiple homeostatic functions and play an essential role in the expression of normal sleep-wake behavior. While their two known receptors (OX(1) and OX(2)) are targets for novel pharmacotherapeutics, the actions mediated by each receptor remain largely unexplored. Usi...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3869224/ https://ncbi.nlm.nih.gov/pubmed/24391530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2013.00246 |
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