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Differential Roles of Orexin Receptor-1 and -2 in the Regulation of Non-REM and REM Sleep

Orexin-A and orexin-B are hypothalamic neuropeptides that play critical roles in the maintenance of wakefulness. Intracerebroventricular (ICV) administration of orexin-A has been shown to promote wakefulness and suppress both rapid eye movement (REM) sleep and non-REM (NREM) sleep through the orexin...

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Detalhes bibliográficos
Main Authors: Mieda, Michihiro, Hasegawa, Emi, Kisanuki, Yaz Y., Sinton, Christopher M., Yanagisawa, Masashi, Sakurai, Takeshi
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732784/
https://ncbi.nlm.nih.gov/pubmed/21525292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6506-10.2011
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