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Orexin peptides prevent cataplexy and improve wakefulness in an orexin neuron-ablated model of narcolepsy in mice

Narcolepsy-cataplexy is a neurological disorder associated with the inability to maintain wakefulness and abnormal intrusions of rapid eye movement sleep-related phenomena into wakefulness such as cataplexy. The vast majority of narcoleptic-cataplectic individuals have low or undetectable levels of...

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Autors principals: Mieda, Michihiro, Willie, Jon T., Hara, Junko, Sinton, Christopher M., Sakurai, Takeshi, Yanagisawa, Masashi
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC384801/
https://ncbi.nlm.nih.gov/pubmed/15070772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400590101
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