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Orexin peptides prevent cataplexy and improve wakefulness in an orexin neuron-ablated model of narcolepsy in mice

Narcolepsy-cataplexy is a neurological disorder associated with the inability to maintain wakefulness and abnormal intrusions of rapid eye movement sleep-related phenomena into wakefulness such as cataplexy. The vast majority of narcoleptic-cataplectic individuals have low or undetectable levels of...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Mieda, Michihiro, Willie, Jon T., Hara, Junko, Sinton, Christopher M., Sakurai, Takeshi, Yanagisawa, Masashi
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2004
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC384801/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15070772/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0400590101
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