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Orexin neurons suppress narcolepsy via 2 distinct efferent pathways

The loss of orexin neurons in humans is associated with the sleep disorder narcolepsy, which is characterized by excessive daytime sleepiness and cataplexy. Mice lacking orexin peptides, orexin neurons, or orexin receptors recapitulate human narcolepsy phenotypes, further highlighting a critical rol...

詳細記述

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書誌詳細
主要な著者: Hasegawa, Emi, Yanagisawa, Masashi, Sakurai, Takeshi, Mieda, Michihiro
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904620/
https://ncbi.nlm.nih.gov/pubmed/24382351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI71017
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