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Orexin neurons suppress narcolepsy via 2 distinct efferent pathways

The loss of orexin neurons in humans is associated with the sleep disorder narcolepsy, which is characterized by excessive daytime sleepiness and cataplexy. Mice lacking orexin peptides, orexin neurons, or orexin receptors recapitulate human narcolepsy phenotypes, further highlighting a critical rol...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hasegawa, Emi, Yanagisawa, Masashi, Sakurai, Takeshi, Mieda, Michihiro
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904620/
https://ncbi.nlm.nih.gov/pubmed/24382351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI71017
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