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Orexin neurons suppress narcolepsy via 2 distinct efferent pathways
The loss of orexin neurons in humans is associated with the sleep disorder narcolepsy, which is characterized by excessive daytime sleepiness and cataplexy. Mice lacking orexin peptides, orexin neurons, or orexin receptors recapitulate human narcolepsy phenotypes, further highlighting a critical rol...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3904620/ https://ncbi.nlm.nih.gov/pubmed/24382351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI71017 |
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