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Narcoleptic orexin receptor knockout mice express enhanced cholinergic properties in laterodorsal tegmental neurons
Pharmacological studies of narcoleptic canines indicate that exaggerated pontine cholinergic transmission promotes cataplexy. Since disruption of orexin (hypocretin) signaling is a primary defect in narcolepsy with cataplexy, we investigated whether markers of cholinergic synaptic transmission might...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2945818/ https://ncbi.nlm.nih.gov/pubmed/20576035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2010.07259.x |
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