Narcoleptic orexin receptor knockout mice express enhanced cholinergic properties in laterodorsal tegmental neurons

Pharmacological studies of narcoleptic canines indicate that exaggerated pontine cholinergic transmission promotes cataplexy. Since disruption of orexin (hypocretin) signaling is a primary defect in narcolepsy with cataplexy, we investigated whether markers of cholinergic synaptic transmission might...

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Detaylı Bibliyografya
Asıl Yazarlar: Kalogiannis, M., Grupke, S.L., Potter, P.E., Edwards, J.G., Chemelli, R.M., Kisanuki, Y.Y., Yanagisawa, M., Leonard, C.S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945818/
https://ncbi.nlm.nih.gov/pubmed/20576035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2010.07259.x
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