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Cholinergic Modulation of Narcoleptic Attacks in Double Orexin Receptor Knockout Mice
To investigate how cholinergic systems regulate aspects of the sleep disorder narcolepsy, we video-monitored mice lacking both orexin (hypocretin) receptors (double knockout; DKO mice) while pharmacologically altering cholinergic transmission. Spontaneous behavioral arrests in DKO mice were highly s...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3076437/ https://ncbi.nlm.nih.gov/pubmed/21533254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018697 |
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